Custom Modifications
Most cell disruption procedures can be handled readily in the
920 mL, 4635 Vessel with its customary fittings and attachments,
yet applications may arise in which it will be desirable to modify
a vessel to meet special requirements. If initial studies show a
need for modifications, the user can return any vessel to the
factory for such changes or additions as may be needed.
Changes sometimes requested include:
Multiple sample capacity.
Up to three additional dip tubes
and discharge valves can be installed in any vessel (except the
45 mL size). With these additional outlets and appropriate sample
holders, as many as four samples can be processed indepen-
dently and simultaneously in a single unit.
Special valves.
Valves with either larger or smaller orifices
can be provided. Users processing large quantities of materials
that have a tendency to plug the orifice of the standard throttling
valve may want to substitute either a larger needle valve or
a ball valve to permit faster flow rates or to avoid stoppage.
Fine metering valves with smaller orifices and very precise
control capabilities may be helpful when treating samples that
must be processed under very exact and repeatable conditions.
Such valves may also be desirable when working with very
small samples.
Size conversion.
Since cylinders for the 920 and 1850 mL
vessels are interchangeable and both vessels use the same head
and closure, any user of a 4635 Vessel can increase the capacity
of his unit to the 4636 size by simply purchasing a deeper
cylinder (599HC22) and a longer dip tube (592HC5). A similar
conversion can also be made from the one gallon vessel to the
two gallon size for users interested in vaccine production or in
similar large volume applications. These larger vessels can also
be equipped with vigorous internal agitators to speed equilibrium
times when processing large volumes of material.
Inquiries concerning any of these modifications should be
directed to Parr Instrument Company Customer Service.
Easy Access To Vessel Chamber
Each of these vessels, except the small 45 mL size, has a split-
ring closure – an exclusive Parr design which allows the vessel to
be opened or closed easily without disturbing any of the fittings
or connecting lines attached to the head. In this closure two ring
sections slide into place from the sides of the vessel to lock the
head in position while a self-sealing O-ring maintains a tight seal
at all pressures. The ring sections are secured by a latch mech-
anism that is connected to the split rings.
On the small, 45 mL vessel, a firm closure is obtained by
simply turning down a knurled cap until it is hand tight. No
wrenches or fixtures are required.
Safety Protection
All Parr Cell Disruption Vessels are designed to accommodate
a commercial nitrogen cylinder. The 920 mL and 1850 mL vessels
are protected by a safety rupture disc which will burst at approxi-
mately 3000 psig, well below the pressure at which any parts
of the vessel would fail. The 1 and 2 Gallon O-ring vessels are
protected by 2200 psig rupture disc to protect the assembly as
this is the maximum allowable working pressure for its compo-
nents. The flat gasket seal version of the 1 and 2 Gallon is rated
at 1900 psig and is protected by a rupture disc of the same rating.
A 3000 psi pressure gage is standard, but other gages as well as
rupture discs with lower pressure ratings can be furnished on
special order. The 45 mL does not include any additional safety
devices and is rated for a maximum 2900 psig for use with a
full nitrogen tank.
Includes Nitrogen Filling Connection
An 1831 Nitrogen Filling Connection furnished with each
vessel provides all of the fittings needed to fill the vessel from a
commercial nitrogen cylinder. The 1831 Connection consists of a
control valve with a standard CGA-580 coupling for attachment
to a nitrogen cylinder, a tank pressure gage and a flexible Nylon
pressure hose for connection to the vessel inlet valve. Extra
O-rings for the vessel head are included with each vessel.
Ordering
Information
Orders for these vessels should specify
the catalog number and internal volume
of the vessel as shown in the following
table. Each vessel will be made of an AISI
300-series stainless steel and equipped
with a 0-3000 psi pressure gage and 1831
Nitrogen Filling Connection, unless other
construction and other fittings are specified.
Parr Cell Disruption Vessels
Inside
Inside
Catalog Internal
Maximum Maximum Working Diameter
Depth
Number Volume Sample Size Pressure, psig (bar)
Inches
Inches
4639
45 mL
30 mL
2900* (200)
1.50
2.25
4635
920 mL 600 mL
3000 (200)
3.75
5.10
4636
1850 mL 1200 mL
3000 (200)
3.75
10.10
4637**
1 gallon 2.5 liters
2200 (152)
6.00
8.60
4638**
2 gallon 5.0 liters
2200 (152)
6.00
17.20
* MAWP of 2900 psig is intended for maximum pressure of nitrogen fill tank
** O-ring only. Optional flat gasket design rates 1900 psi MAWP.
P a r r I n s t r u m e n t C o m p a n y
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Cell Disruption Vessels
